preprints_ui: 3dmrx_v1
Data license: ODbL (database) & original licenses (content) · Data source: Open Science Framework
| id | title | description | date_created | date_modified | date_published | original_publication_date | publication_doi | provider | is_published | reviews_state | version | is_latest_version | preprint_doi | license | tags_list | tags_data | contributors_list | contributors_data | first_author | subjects_list | subjects_data | download_url | has_coi | conflict_of_interest_statement | has_data_links | has_prereg_links | prereg_links | prereg_link_info | last_updated |
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| 3dmrx_v1 | An infection model for severe COVID-19 | We wish to propose an infection model to address some of the unique and unusual features observed in COVID-19, eg. why were severe patients mounting more intense immune response compared to the mild cases, why did severe patients demonstrate higher and more protracted viral shedding when the immune response was greater, etc. In this exposition, we will first describe a generic acute viral infection framework based on work done mainly in influenza infection to understand the acute infective cycle, then contrast it with COVID-19 data to highlight main differences to construct a pathogenic model, and finally extrapolate to discuss applications in potential therapeutic considerations. | 2020-10-16T09:55:45.257505 | 2020-10-19T13:44:56.496122 | 2020-10-16T10:05:28.745841 | nutrixiv | 0 | withdrawn | 1 | 1 | https://doi.org/10.31232/osf.io/3dmrx | No license | COVID-19; Magnesium; Vitamin B12; Vitamin D | ["COVID-19", "Magnesium", "Vitamin B12", "Vitamin D"] | Ho P; Tan Chuen Wen; Jason Chay Wai Mun; Chandramouli Nagarajan; Ng Heng Joo | [{"id": "w9cqg", "name": "Ho P", "index": 0, "orcid": null, "bibliographic": true}, {"id": "myvkb", "name": "Tan Chuen Wen", "index": 1, "orcid": null, "bibliographic": true}, {"id": "pfrt2", "name": "Jason Chay Wai Mun", "index": 2, "orcid": null, "bibliographic": true}, {"id": "qhkgm", "name": "Chandramouli Nagarajan", "index": 3, "orcid": null, "bibliographic": true}, {"id": "ec36p", "name": "Ng Heng Joo", "index": 4, "orcid": null, "bibliographic": true}] | Ho P | Medicine and Health Sciences; Diseases; Nutritional and Metabolic Diseases | [{"id": "59baca0954be810322d96d4e", "text": "Medicine and Health Sciences"}, {"id": "59baca0954be810322d96d53", "text": "Diseases"}, {"id": "59baca0954be810322d96d5d", "text": "Nutritional and Metabolic Diseases"}] | 0 | not_applicable | not_applicable | [] | 2025-04-09T20:04:19.169167 |