preprints_ui: desyu_v1
Data license: ODbL (database) & original licenses (content) · Data source: Open Science Framework
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| desyu_v1 | An 18-month meditation training selectively improves psychological well-being in older adults | Objectives: As the world population is ageing, it is vital to understand how older adults can maintain and deepen their psychological well-being as they are confronted with the unique challenges of ageing in a complex and vulnerable world. Theoretical work has highlighted the promising role of intentional mental training such as meditation practice for enhancing human flourishing. However, meditation-based randomised controlled trials in older adults are lacking. We aimed to investigate the effects of meditation training on psychological well-being in older adults. Methods: The Age-Well trial (ClinicalTrials.gov: NCT02977819) randomised 137 healthy older adults to an 18-month meditation training (9-month mindfulness followed by 9-month compassion and loving-kindness training), a structurally matched active comparator (English language training), or a passive control. Well-being was measured at baseline, mid-intervention, and 18-month post-randomisation using the Psychological Well-being Scale (PWBS), the World Health Organisation’s Quality of Life (QoL) Assessment psychological subscale, and composite scores reflecting meditation-based well-being dimensions of awareness, connection, insight, and a global score comprising the average of these three meditation-based dimensions. Mixed effects models assessed between- and within-group differences in change over 18 months. Results: Meditation training was superior to English training on changes in the global score and the subscales of awareness, connection, insight, and superior to no-intervention only on changes in the global score and awareness. Between-group differences in psychological QoL in favour of meditation did not remain significant after adjusting for multiple comparisons. There were no between-group differences in PWBS total score. Within the meditation group, psychological QoL, awareness, insight, and the global score increased significantly from baseline to 18-month post-randomisation. Exploratory moderator analyses suggested that greater levels of well-being at baseline predicted smaller improvements for most well-being outcomes. Conclusion: The longest randomised meditation training conducted to date enhanced a global composite score reflecting the meditation-based well-being dimensions of awareness, connection, and insight in older adults. Future research is needed to delineate the cognitive, affective, and behavioural factors that predict responsiveness to meditation and thus help refine the development and efficacy of tailored meditation-based interventions. | 2022-10-20T12:38:52.467931 | 2022-11-01T05:02:22.194142 | 2022-10-31T15:17:58.021609 | mindrxiv | 1 | accepted | 1 | 1 | https://doi.org/10.31231/osf.io/desyu | CC-By Attribution 4.0 International | [] | Marco Schlosser; olga klimecki; Fabienne Collette; Julie Gonneaud; Matthias Kliegel; Natalie L. Marchant; Gaël Chételat; Antoine Lutz | [{"id": "wgejf", "name": "Marco Schlosser", "index": 0, "orcid": "", "bibliographic": true}, {"id": "s7gmr", "name": "olga klimecki", "index": 1, "orcid": "0000-0003-0757-7761", "bibliographic": true}, {"id": "v2j8n", "name": "Fabienne Collette", "index": 2, "orcid": "0000-0001-9288-9756", "bibliographic": true}, {"id": "hs47m", "name": "Julie Gonneaud", "index": 3, "orcid": null, "bibliographic": true}, {"id": "nmpw2", "name": "Matthias Kliegel", "index": 4, "orcid": "0000-0002-2001-2522", "bibliographic": true}, {"id": "hv3ts", "name": "Natalie L. Marchant", "index": 5, "orcid": "0000-0003-0669-6910", "bibliographic": true}, {"id": "zjqd2", "name": "Ga\u00ebl Ch\u00e9telat", "index": 6, "orcid": null, "bibliographic": true}, {"id": "4dwkm", "name": "Antoine Lutz", "index": 7, "orcid": null, "bibliographic": true}] | Marco Schlosser | Medicine and Health Sciences; Social and Behavioral Sciences; Psychiatry and Psychology; Mental and Social Health; Psychology; Psychological Phenomena and Processes; Health Psychology; Psychiatric and Mental Health | [{"id": "59bacc2a54be8103332cb78b", "text": "Medicine and Health Sciences"}, {"id": "59bacc2a54be8103332cb78f", "text": "Social and Behavioral Sciences"}, {"id": "59bacc2a54be8103332cb7a5", "text": "Psychiatry and Psychology"}, {"id": "59bacc2b54be8103332cb7d0", "text": "Mental and Social Health"}, {"id": "59bacc2b54be8103332cb7d5", "text": "Psychology"}, {"id": "59bacc2b54be8103332cb7d7", "text": "Psychological Phenomena and Processes"}, {"id": "59bacc2c54be8103332cb804", "text": "Health Psychology"}, {"id": "59bacc2c54be8103332cb807", "text": "Psychiatric and Mental Health"}] | https://osf.io/download/6351417993d3520c6591bbc1 | 1 | GC has received research support from the EU’s Horizon 2020 research and innovation programme (grant agreement number 667696), Inserm, Fondation d’entreprise MMA des Entrepreneurs du Futur, Fondation Alzheimer, Programme Hospitalier de Recherche Clinique, Région Normandie, Association France Alzheimer et maladies apparentées and Fondation Vaincre Alzheimer (all to Inserm), and personal fees from Fondation d’entreprise MMA des Entrepreneurs du Futur. All other authors have no relevant financial or non-financial interests to disclose. | no | available | ["https://clinicaltrials.gov/ct2/show/NCT02977819"] | prereg_designs | 2025-04-09T20:50:08.800351 |