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id title description date_created date_modified date_published original_publication_date publication_doi provider is_published reviews_state version is_latest_version preprint_doi license tags_list tags_data contributors_list contributors_data first_author subjects_list subjects_data download_url has_coi conflict_of_interest_statement has_data_links has_prereg_links prereg_links prereg_link_info last_updated
sjz4e_v1 HistoEnder: a 3D printer-based histological slide autostainer that retains 3D printer functions Automated microscope slide stainers are usually very expensive and unless the laboratory performs heavy histological work it is difficult to justify buying a 2000-10000€ machine. As a result, histology and pathology labs around the world lose thousands of working hours for following procedures that could be easily automated. Herein, we propose a simple modification of an open-source 3D printer, the Creality Ender-3, into an automated microscope slide autostainer, the HistoEnder. The HistoEnder is cheap (less than 200€), modular, and easy to set up, with only two 3D-printed parts needed. Additionally, the 3D printer retains its full functionality, and it can be reverted back into 3D printing in less than 1 minute. The g-code associated with the procedure is extremely simple, and can be written by anyone. The HistoEnder can also be used in chemistry and material science laboratories for automating surface modifications and dip coating. 2022-01-19T18:49:05.161854 2022-03-01T18:52:19.502287 2022-01-19T19:07:40.546595     engrxiv 0 withdrawn 1 1 https://doi.org/10.31224/osf.io/sjz4e CC-By Attribution 4.0 International dip-coating; haematoxylin eosin; histoender; histology; pathology; slide autostainer ["dip-coating", "haematoxylin eosin", "histoender", "histology", "pathology", "slide autostainer"] Marco Ponzetti; Ganga Chinna Rao Devarapu; Nadia Rucci; Armando Carlone; Vittorio Saggiomo [{"id": "qsa28", "name": "Marco Ponzetti", "index": 0, "orcid": "0000-0002-7554-1325", "bibliographic": true}, {"id": "v4u8c", "name": "Ganga Chinna Rao Devarapu", "index": 1, "orcid": null, "bibliographic": true}, {"id": "zqfsv", "name": "Nadia Rucci", "index": 2, "orcid": null, "bibliographic": true}, {"id": "yz2d8", "name": "Armando Carlone", "index": 3, "orcid": null, "bibliographic": true}, {"id": "zebd6", "name": "Vittorio Saggiomo", "index": 4, "orcid": "0000-0001-7196-602X", "bibliographic": true}] Marco Ponzetti Engineering; Biomedical Engineering and Bioengineering; Biomedical Devices and Instrumentation [{"id": "5994df7a54be8100732d43ae", "text": "Engineering"}, {"id": "5994df7b54be8100732d4401", "text": "Biomedical Engineering and Bioengineering"}, {"id": "5994df7b54be8100732d4405", "text": "Biomedical Devices and Instrumentation"}]   0   not_applicable not_applicable []   2025-04-09T20:03:50.155599
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